I have the sme problem, where is this box that has to be checked? I can't get anything to run on my cd rom as far as autoplay and many of my programs do not run ( locks up) even when I try to run them manually
If you dont have tweak ui you can still change the setting. Go to settings>controlpanel>system select the device manager tab. click the plus next to cd-rom then double click your cd-rom. Select the settings tab and check the auto insert notification.
That should take care of it unless you are having hardware problems.