I cannot see there being any sort of problem.
The V5 will fit into an AGP slot, so he needs one on his mobo 
The V5 uses one of the 12V/5V sockets of the power supply loom (just like what HDD's CDRom's etc use), if there isnt a spare one available the V5 comes with a 'Y' adapter to branch off another device.
V5's are really very long so he needs to check that there is room in his case.
If hes gonna stretch the V5's legs then he should really consider getting a faster CPU.
Other than that I cannot think of much else, apart from the tax that customs may want to whollap him for 
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