You won't burn anything out, so that's not a worry. You may corrupt the drivers (I've done that and the only way to get them back is to remove the dll's from the system folder and reinstall. A plain reinstall won't nec. work.
OTOH - the 2k should do about 180+ without too much strain - but that's with a standard pci speed (33mhz) if you o/c, then you'll have to clock it back proportionally. i.e. I had a 2k @180+ with fsb 100 (pci is at 33). When I o/c to 110 (pci is 10% faster) I had to clock the 2k back 10% - @160+
Funny hw that works out
I call it "No-Pants Wonderday," but it turns out the police just call it "Thursday." Go figure.